MOF-metal nanohybrid-assisted charge transfer amplification for electrochemical biosensing of the MUC1 cancer biomarker

The Analyst 2026

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Authors: Sarita Devi, Shivangi Goel, Sonia Rani, Rudolf J. Schneider, Rishika Rohilla, Surbhi Kumari, Nirmal Prabhakar
DOI: 10.1039/d6an00018e
Cited by: 3
References: 36

Abstract

). The negligible cross-reactivity with interferent biomolecules, rapid response (10-minute equilibrium), regenerability up to 5 cycles, high reproducibility (RSD ∼1-3%), and long-term stability (up to 35 days) further validate the suitability of the proposed MUC1 immunosensor. This study presents an ultrasensitive biosensor that is compact, cost-effective, and easy for individuals at home to use after further development into a kit-based end product. Moreover, its excellent functionality for spiked serum samples shows promise for next-generation clinical diagnostics.

Fields of Study & Subjects

Advanced biosensing and bioanalysis techniques Electrochemical sensors and biosensors Metal-Organic Frameworks: Synthesis and Applications

Publication details

Journal / source
The Analyst
Publisher
Royal Society of Chemistry (RSC)
Volume
151
Issue
8
Pages
2379–2389
Publication date
1 January 2026
Language
EN