Development of a surface enhanced Raman scattering lateral flow immunoassay with prolonged reproducibility and stability over time

The Analyst 2026 Open access

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Authors: Sian Sloan-Dennison, Ben Clark, Kathleen M Scullion, Fiona Smillie, Stacey Laing, Paul Fineran, Joanne Mair, Cicely Rathmell, Dieter Bingemann, Jonathan Faircloth, D. J. Creasey, Neil C. Shand
+4 more Christopher J. Weir, James W. Dear, Duncan Graham, Karen Faulds
DOI: 10.1039/d6an00053c
Cited by: 3
References: 25

Abstract

the slope linear regression method. After 5 months the output only decreased by 11% for a sample spiked with a clinically relevant concentration of liver injury biomarker, demonstrating the test was still performing as intended. Overall, we have shown that SERS-LFIA can produce similar outputs after 5 months of storage at room temperature demonstrating their stability and robustness.

Fields of Study & Subjects

Biosensors and Analytical Detection Gold and Silver Nanoparticles Synthesis and Applications Innovative Microfluidic and Catalytic Techniques Innovation

Publication details

Journal / source
The Analyst
Publisher
Royal Society of Chemistry (RSC)
Volume
151
Issue
11
Pages
3130–3140
Publication date
1 January 2026
Language
EN