Study on the detection of prostate cancer using MIRA-CRISPR/Cas12a technology

Analytical Methods 2026

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Authors: Yuanyuan Chen, Daiyan Tang, Jin Zhan, Yiyao Wang, Zhen Song
DOI: 10.1039/d6ay00025h
Cited by: 1
References: 62

Abstract

: the MIRA-CRISPR/Cas12a technology enables specific detection of PCA3 molecules in urine. This technique features high sensitivity, high specificity, visual results, and simple operation. It does not require specialized laboratory UV imaging equipment; results are visible to the naked eye under LED blue light. Following further optimization, it offers a feasible technical solution for rapid molecular screening of prostate cancer.

Fields of Study & Subjects

CRISPR and Genetic Engineering Prostate Cancer Treatment and Research Single-cell and spatial transcriptomics

Publication details

Journal / source
Analytical Methods
Publisher
Royal Society of Chemistry (RSC)
Volume
18
Issue
18
Pages
3848–3857
Publication date
1 January 2026
Language
EN