A novel peroxidase-mimicking Cu,S co-doped carbon dot nanozyme for dual-mode lactate biosensing in serum and sweat
Abstract
generated by lactate oxidase. The produced pink chromogenic compound not only caused efficient quenching of the Cu-S@CDs fluorescence for fluorometric analysis, but also provided a characteristic absorbance signal at 512 nm for colorimetric measurement. With optimized experimental parameters, the fluorometric assay demonstrated a linear range of 0.02-800 µM, whereas the colorimetric assay showed a linear range of 0.1-750 µM. Application of the developed method to serum and sweat samples produced consistent analytical performance, underscoring its suitability for clinical diagnostic use and tailored health monitoring.
Fields of Study & Subjects
Advanced Nanomaterials in Catalysis
Carbon and Quantum Dots Applications
Electrochemical sensors and biosensors
Publication details
- Journal / source
- Analytical Methods
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 18
- Issue
- 21
- Pages
- 4387–4399
- Publication date
- 1 January 2026
- Language
- EN