A pathogen-activated DNAzyme triggers hybridization chain reaction for ultra-sensitive salivary detection of Helicobacter pylori

Analytical Methods 2026

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Authors: Qiming Chen, Quanling Dong, Zhengrong Lu, Zhanmin Liu
DOI: 10.1039/d6ay00648e
Cited by: 1
References: 28

Abstract

and enables direct analysis of saliva supernatants without complex pretreatment. Recovery studies in artificially contaminated saliva samples show satisfactory accuracy (98.4-104.9%) and reproducibility (RSD < 5%). Owing to its simplified workflow, minimal equipment requirement, and modular design, this strategy provides a generalizable sensing framework for non-invasive pathogen detection.

Fields of Study & Subjects

Helicobacter pylori-related gastroenterology studies Advanced biosensing and bioanalysis techniques RNA regulation and disease

Publication details

Journal / source
Analytical Methods
Publisher
Royal Society of Chemistry (RSC)
Volume
18
Issue
23
Pages
4795–4804
Publication date
1 January 2026
Language
EN