Hydrogel–exosome synergistic system: mechanisms, applications and future prospects in regenerative medicine

Biomaterials Science 2026

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Authors: Bin Xie, Yuyi Kang, Shuihao Zhao, Zhiyun Wu, Zelin Wu, Xiubin Kuang, Jiahong Jiang, Nuo Xu, Xudong Lin, Jun Wu, Tak Man Wong, Shaoquan Bian
+2 more Xiaoli Zhao, Zhengqiang Yuan
DOI: 10.1039/d6bm00274a
Cited by: 1
References: 201

Abstract

, pH, temperature) to control exosome release, optimizing the therapeutic efficacy. Additionally, exosome engineering for enhanced cargo loading and targeting capabilities further advances precision regenerative medicine. This review explores the latest progress, challenges, and future directions in harnessing hydrogels and exosomes for recently developed regenerative medicine and therapeutic applications.

Fields of Study & Subjects

Extracellular vesicles in disease 3D Printing in Biomedical Research Hydrogels: synthesis properties applications

Publication details

Journal / source
Biomaterials Science
Publisher
Royal Society of Chemistry (RSC)
Volume
14
Issue
12
Pages
3049–3081
Publication date
1 January 2026
Language
EN