De novo grafted coiled-coil peptides as p53/ h DM2 inhibitors

RSC Chemical Biology 2026 Open access

Read full text
Authors: Freya Spain, Diana Gimenez, Amanda M. Acevedo‐Jake, Bram Mylemans, Nikolas J. Brooks, Bogusława Korona, Danny T. C. Huang, Thomas A. Edwards, Aneika C. Leney, Laura S. Itzhaki, Derek N. Woolfson, Andrew John Wilson
DOI: 10.1039/d6cb00063k
Cited by: 1
References: 50

Abstract

DM2 PPI with sub-micromolar (μM) affinities, as demonstrated by fluorescence anisotropy.

Fields of Study & Subjects

Cancer-related Molecular Pathways RNA Interference and Gene Delivery Protein Degradation and Inhibitors

Publication details

Journal / source
RSC Chemical Biology
Publisher
Royal Society of Chemistry (RSC)
Volume
7
Issue
8
Pages
1589–1596
Publication date
1 January 2026
Language
EN