peri -Selective C–H activation-initiated spiroannulation leading to spiropolycyclic compounds with unique photophysical properties and strong anticancer activity

Chemical Communications 2026

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Authors: Qianting Zhou, Jiayi Zou, Haiyun Xu, Yijun Gong, Chunhua Ma, Xinying Zhang, Xuesen Fan
DOI: 10.1039/d6cc00372a
Cited by: 1
References: 46

Abstract

Presented herein is a peri -selective spiroannulation of 3-(naphthalen-1-yl)-2 H -indazoles with cyclic diazo compounds leading to the formation of benzo[ de ]isoquinoline spiroisoquinolinone and benzo[ de ]isoquinoline spironaphthalenone derivatives.

Fields of Study & Subjects

Catalytic C–H Functionalization Methods Radical Photochemical Reactions Cyclopropane Reaction Mechanisms

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
37
Pages
9486–9490
Publication date
1 January 2026
Language
EN