A single heteroatom controls halogen- versus chalcogen-bond-driven cellular uptake

Chemical Communications 2026

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Authors: Debasish Giri, Ekta Chauhan, Govindasamy Mugesh
DOI: 10.1039/d6cc00396f
Cited by: 0
References: 26

Abstract

Halogen and chalcogen bonds can both promote membrane recognition and here we demonstrate that within the same scaffold, oxygen analogues exhibit halogen-dependent uptake, whereas sulfur and selenium analogues rely mainly on chalcogen bonding.

Fields of Study & Subjects

Crystallography and molecular interactions Supramolecular Chemistry and Complexes Molecular Sensors and Ion Detection

Publication details

Journal / source
Chemical Communications
Volume
62
Issue
25
Pages
6763–6767
Publication date
1 January 2026
Language
EN