PyTTA-HOF/MXene integration with a CRISPR/Cas12 strategy for advanced homogeneous photoelectrochemical sensing

Chemical Communications 2026

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Authors: Huili Yu, Jiale Wang, Qin-xia Du, Li-Ping Jia, Wei Zhang, Lei Shang, Xiao-Jian Li, Huai-Sheng Wang, Rong-Na Ma
DOI: 10.1039/d6cc00429f
Cited by: 2
References: 33

Abstract

An advanced homogeneous photoelectrochemical (PEC) sensing strategy is designed based on the integration of the excellent PEC performance of PyTTA-HOF/MXene with CRISPR/Cas12a-mediated signal transduction and amplification, which can effectively avoid cumbersome, multi-step electrode modification and demonstrates satisfactory detection performance for the clinically relevant HPV-16 gene.

Fields of Study & Subjects

CRISPR and Genetic Engineering Advanced biosensing and bioanalysis techniques MXene and MAX Phase Materials

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
22
Pages
6118–6122
Publication date
1 January 2026
Language
EN