Photosensitizer-free polarity-mismatched electrophilic α,α-bis-functionalization of acetone with quinoxaline and maleimide
Abstract
A polarity-mismatch-driven, photosensitizer-free protocol for the α,α-bis-functionalization of acetone has been developed, employing quinoxaline and maleimide as coupling partners. The photoactive species is identified as the ion-pair complex of protonated 2-phenylquinoxaline with methanesulfonate, wherein photoinduced electron transfer (PET) serves as the key mechanistic pathway. To the best of our knowledge, this is a unique photo-induced α,α-bisfunctionalization of acetone.
Fields of Study & Subjects
Radical Photochemical Reactions
Photochemistry and Electron Transfer Studies
Cyclopropane Reaction Mechanisms
Publication details
- Journal / source
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 62
- Issue
- 15
- Pages
- 4561–4564
- Publication date
- 1 January 2026
- Language
- EN