Ultrasound-driven sonodynamic therapy for hepatocellular carcinoma
Abstract
Hepatocellular carcinoma (HCC) is characterized by high malignancy, high recurrence rate and poor prognosis. Existing treatment still faces challenges such as insufficient precision, limited efficacy, and significant side effects, and there is an urgent need for developing novel therapies. Sonodynamic therapy (SDT) has emerged as a promising alternative to conventional cancer therapies by using ultrasound to activate sonosensitizers and generate reactive oxygen species. This review aims to establish a foundation and guide future investigations toward the clinical application of SDT in HCC management.
Fields of Study & Subjects
Ultrasound and Hyperthermia Applications
Hepatocellular Carcinoma Treatment and Prognosis
Photoacoustic and Ultrasonic Imaging
Publication details
- Journal / source
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 62
- Issue
- 19
- Pages
- 5405–5411
- Publication date
- 1 January 2026
- Language
- EN