Phosphine-catalyzed sequential [4+1]/[2+3] annulation of o -amino arylaldimines with Morita–Baylis–Hillman (MBH) carbonates
Abstract
We report a strategy to access hexahydropyrrolo[3,2- b ]indoles bearing three consecutive stereocenters from o -amino arylaldimines with MBH carbonates under phosphine catalysis.
Fields of Study & Subjects
Catalytic C–H Functionalization Methods
Asymmetric Synthesis and Catalysis
Synthesis of heterocyclic compounds
Publication details
- Journal / source
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 62
- Issue
- 31
- Pages
- 8013–8017
- Publication date
- 1 January 2026
- Language
- EN