Phosphine-catalyzed sequential [4+1]/[2+3] annulation of o -amino arylaldimines with Morita–Baylis–Hillman (MBH) carbonates

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Authors: Xianfei Hu, Xing Qu, Zhiyue Li, Lishuang Wang, Hui Yao, Linxuan Li, ZhongYan Cao, Nianyu Huang, Nengzhong Wang
Cited by: 7
References: 47

Abstract

We report a strategy to access hexahydropyrrolo[3,2- b ]indoles bearing three consecutive stereocenters from o -amino arylaldimines with MBH carbonates under phosphine catalysis.

Fields of Study & Subjects

Catalytic C–H Functionalization Methods Asymmetric Synthesis and Catalysis Synthesis of heterocyclic compounds

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
31
Pages
8013–8017
Publication date
1 January 2026
Language
EN