Diastereoselective intramolecular O -allylation with alkynes using palladium/Brønsted acid combined catalysis: access to substituted chiral oxazolidines
Abstract
-tethered alkynes has been developed. The reaction utilizes Brønsted acid as a co-catalyst and provides a completely atom-economic pathway to access functionalized chiral oxazolidines. Moreover, the enantiomerically pure substrates have been derived from simple, inexpensive chiral amino alcohols.
Fields of Study & Subjects
Catalytic C–H Functionalization Methods
Catalytic Alkyne Reactions
Asymmetric Synthesis and Catalysis
Publication details
- Journal / source
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 62
- Issue
- 18
- Pages
- 5289–5292
- Publication date
- 1 January 2026
- Language
- EN