Pd-catalyzed enantio- and diastereoselective synthesis of N–N atropisomeric indoles via N -alkylation reaction

Chemical Communications 2026

View at publisher
Authors: Xiao Lu, Yongqiang Xu, Wenkai Li, Yuhan Zhou, Jingping Qu, Baomin Wang
DOI: 10.1039/d6cc00641h
Cited by: 2
References: 37

Abstract

-alkylation reaction, featuring good substrate tolerance and high yield with high enantio- and diastereoselectivity. Furthermore, the synthetic utility of the protocol was demonstrated by large-scale reaction and transformation of the product.

Fields of Study & Subjects

Axial and Atropisomeric Chirality Synthesis Catalytic C–H Functionalization Methods Catalytic Alkyne Reactions

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
28
Pages
7385–7388
Publication date
1 January 2026
Language
EN