Palladium-catalyzed denitrative C–N coupling of amides with nitroarenes enabled by Al(OTf) 3

Chemical Communications 2026 Open access

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Authors: Linjie Yang, Xuejie Wang, Wanzhi Chen
DOI: 10.1039/d6cc00697c
Cited by: 3
References: 31

Abstract

Pd-catalyzed denitrative C–N coupling of amides with nitroarenes enables direct, atom-economical access to N -aryl amides. Catalytic Al(OTf) 3 acts as a Lewis acid and suppresses BrettPhos oxidation, preserving the active Pd–phosphine species.

Fields of Study & Subjects

Catalytic C–H Functionalization Methods Catalytic Cross-Coupling Reactions Advanced Synthetic Organic Chemistry

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
29
Pages
7615–7618
Publication date
1 January 2026
Language
EN