Detection of reactive oxygen species associated with photodynamic therapy

Chemical Communications 2026

View at publisher
Authors: Ming-chen Xiong, Li‐Ya Niu, Kun‐Xu Teng, Qing‐Zheng Yang
DOI: 10.1039/d6cc00750c
Cited by: 4
References: 75

Abstract

Accurate detection of reactive oxygen species (ROS) associated with photodynamic therapy (PDT) is essential for evaluating the performance of photosensitizers and elucidating PDT mechanisms. This review systematically evaluates the detection of ROS related to PDT using commercially available probes, including singlet oxygen, superoxide anion radicals, hydroxyl radicals, hydrogen peroxide, and peroxynitrite. We compare their structures, detection mechanisms, performance, advantages, and limitations, and offer practical guidance to help researchers select appropriate ROS detection strategies for PDT studies.

Fields of Study & Subjects

Photodynamic Therapy Research Studies Nanoplatforms for cancer theranostics Skin Protection and Aging

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
32
Pages
8079–8088
Publication date
1 January 2026
Language
EN