Desaturative arylaldehyde synthesis by synergistic carbocatalysis and organocatalysis

Chemical Communications 2026 Open access

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Authors: Naokatsu Kannari, Ivan Curic, Nina Place, Lukas Enders, Shotaro Kawasaki, Anna Lenarda, Juho Helaja
DOI: 10.1039/d6cc00868b
Cited by: 2
References: 49

Abstract

A metal-free cooperative carbocatalyst-organocatalyst system promotes the dehydrogenative aromatization of 3-cyclohexene aldehydes to aromatic aldehydes. Quinone-rich, oxidized activated carbon and secondary amines act synergistically, providing a structurally diverse substrate scope. Mechanistic studies indicate a predominantly ionic hydride-transfer pathway and identify pore-blocking as the main cause of catalyst deactivation.

Fields of Study & Subjects

Catalytic C–H Functionalization Methods Oxidative Organic Chemistry Reactions Asymmetric Hydrogenation and Catalysis

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
33
Pages
8476–8480
Publication date
1 January 2026
Language
EN