Enantioselective Pd&Cu-catalyzed coupling of imine esters with gem -difluorinated cyclopropanes

Chemical Communications 2026

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Authors: Deyue Ren, Jie Zhao, Jin-Tao Xia, He Zhang, Yingchun Qiu, Ziqi Yu, Jinping Hu, Tianhao Li, Fang Xie
DOI: 10.1039/d6cc00880a
Cited by: 1
References: 47

Abstract

This work details a Pd/Cu-cocatalyzed coupling of imine esters with gem -difluorinated cyclopropanes to access enantiomerically enriched α-quaternary 2-fluoroallylic 2 H -pyrroles.

Fields of Study & Subjects

Cyclopropane Reaction Mechanisms Fluorine in Organic Chemistry Catalytic C–H Functionalization Methods

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
23
Pages
6360–6363
Publication date
1 January 2026
Language
EN