Boosting the oxidase-mimicking activity of metal–organic framework nanozymes via heteroatom modulation in the organic linkers

Chemical Communications 2026

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Authors: Yan Wei, Qiming Yan, Zizhe Yan, Jie Yang, L. Zhang, Feng Li, Dangqiang Zhu
DOI: 10.1039/d6cc01013j
Cited by: 3
References: 29

Abstract

By replacing the linear terephthalate linker with five-membered heterocyclic analogues, we synthesized a series of MIL-53(Fe) nanozymes. The incorporated heteroatoms (O or S) effectively modulate the electron density of the metal active sites. Consequently, the MIL-53(Fe)-TDC variant exhibits an approximately six-fold enhancement in oxidase-like activity compared to its counterpart MIL-53(Fe)-BDC.

Fields of Study & Subjects

Advanced Nanomaterials in Catalysis Metal-Organic Frameworks: Synthesis and Applications Nanocluster Synthesis and Applications

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
32
Pages
8216–8219
Publication date
1 January 2026
Language
EN