Copper-mediated photoinduced perfluoroalkylation of arylsulfonium salts
Abstract
] reagents for site-selective late-stage perfluoroalkylation of arenes. The protocol displays a broad substrate scope and outstanding functional-group tolerance, accommodating diverse functional moieties, heterocyclic motifs, and complex drug-derived scaffolds. This approach markedly enriches the repertoire of late-stage perfluoroalkylation methods, providing a unified, modular, and chain-length-tunable platform for the construction of perfluoroalkylated compounds with potential applications in materials science, medicinal chemistry, and agrochemical development.
Fields of Study & Subjects
Fluorine in Organic Chemistry
Click Chemistry and Applications
Sulfur-Based Synthesis Techniques
Publication details
- Journal / source
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 62
- Issue
- 32
- Pages
- 8270–8274
- Publication date
- 1 January 2026
- Language
- EN