Dihalogenation/cyclization reactions of bicyclo[1.1.0]butane-1-carboxamide: rapid access to dihalogenated spiro[cyclobutane-1,3′-quinolin]-2′-one derivatives
Abstract
a strain-release reaction has been developed. The reaction features a broad substrate scope, good functional group compatibility, low-cost halogenating reagents, and mild reaction conditions. Moreover, not using any catalysts and an extremely short reaction time (3-5 min) are the most important highlights of this synthesis.
Fields of Study & Subjects
Catalytic Cross-Coupling Reactions
Catalytic C–H Functionalization Methods
Coordination Chemistry and Organometallics
Publication details
- Journal / source
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 62
- Issue
- 43
- Pages
- 10967–10971
- Publication date
- 1 January 2026
- Language
- EN