Silica-based particles for radiation theranostics
Abstract
Theranostics, which integrate diagnosis and therapy within a single platform, are being actively developed worldwide on the basis of functional materials. In this Review, we first outline recent progress in non-porous silica-based platforms that have advanced towards clinical application as therapeutic and theranostic systems, with particular emphasis on imaging-guided radiotherapy and radiosensitisation. We then focus on organosilica nanoparticles as a distinctive class of silica-based particles and summarise their development as cancer theranostic agents. Finally, we discuss opportunities and remaining challenges for translating silica nanomedicine into clinically impactful, chemistry-driven solutions for global health.
Fields of Study & Subjects
Radiation Therapy and Dosimetry
Nanoplatforms for cancer theranostics
Advanced Radiotherapy Techniques
Publication details
- Journal / source
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 62
- Issue
- 47
- Pages
- 11793–11801
- Publication date
- 1 January 2026
- Language
- EN