Diastereoselective assembly of complex benzofuran-annulated spiro-tetrahydroquinoline frameworks via Povarov cyclization
Abstract
a regioselectively reversed Povarov reaction as established through DFT calculations. Broad substrate scope, high functional-group tolerance, and gram-scale applicability are the key highlights of this strategy.
Fields of Study & Subjects
Axial and Atropisomeric Chirality Synthesis
Catalytic Cross-Coupling Reactions
Catalytic C–H Functionalization Methods
Publication details
- Journal / source
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 62
- Issue
- 46
- Pages
- 11627–11631
- Publication date
- 1 January 2026
- Language
- EN