Lewis acid–base interaction-driven phosphodiester hydrolysis in single-atom nanozymes

Chemical Communications 2026

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Authors: Yimeng Wang, Zhiling Zhu, Lina Wang
DOI: 10.1039/d6cc02383e
Cited by: 1
References: 26

Abstract

. In this system, isolated Ce sites act as Lewis acid centers, while adjacent Lewis base domains activate phosphodiester bonds. This interaction lowers the hydrolysis energy barrier, facilitating bond cleavage and inhibiting bacterial biofilm formation.

Fields of Study & Subjects

Advanced Nanomaterials in Catalysis Nanocluster Synthesis and Applications Nanoplatforms for cancer theranostics

Publication details

Journal / source
Chemical Communications
Publisher
Royal Society of Chemistry (RSC)
Volume
62
Issue
47
Pages
11887–11890
Publication date
1 January 2026
Language
EN