Visible-light-induced synthesis of indanones via the annulation of α-hydroxy ketones and alkynes
Abstract
A visible-light-induced annulation of α-hydroxy ketones with alkynes afforded 32 indanones in 30-73% yields under transition-metal- and external-photocatalyst-free conditions. α-Hydroxy ketones serve as the photoactive species, acyl source, and reductant. The strategy was further applied to the synthesis of pauciflorol F, isopauciflorol F, and indatraline.
Fields of Study & Subjects
Radical Photochemical Reactions
Catalytic C–H Functionalization Methods
Sulfur-Based Synthesis Techniques
Publication details
- Journal / source
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 62
- Issue
- 73
- Pages
- 18231–18235
- Publication date
- 1 January 2026
- Language
- EN