Ionic-liquid-assisted aggregation modulation of BODIPY nanoparticles for tunable photodynamic therapy performance

Physical Chemistry Chemical Physics 2026

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Authors: Nayana Nupur Das, Dhanya Rajendrababu, Sudip Gorai, Soumyaditya Mula, Sivan Velmathi, Debashis Majhi
DOI: 10.1039/d6cp01394e
Cited by: 1
References: 59

Abstract

cytotoxicity studies show that the photosensitizer exhibits enhanced cytotoxicity in HeLa cells upon light irradiation, while showing low toxicity in the dark and minimal effects on normal cells. Overall, this work provides molecular and nanoscale-level insights into how ionic-liquid-assisted aggregation and π-conjugation engineering can be combined to tune singlet oxygen generation and photodynamic performance, offering a rational strategy for optimizing BODIPY-based nanoparticle photosensitizers.

Fields of Study & Subjects

Luminescence and Fluorescent Materials Nanoplatforms for cancer theranostics Photodynamic Therapy Research Studies

Publication details

Journal / source
Physical Chemistry Chemical Physics
Publisher
Royal Society of Chemistry (RSC)
Volume
28
Issue
29
Pages
18200–18214
Publication date
1 January 2026
Language
EN