Alleviating effects of 2′-fucosyllactose combined with Bifidobacterium longum BB536 on loperamide-induced constipation and depressive-like behavior

Food & Function 2026

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Authors: Zhongmei Tan, Zihao Tian, Xiaolei Duan, H Steve Zhang, Wei Yu, Qinggang Xie, Dong Xu, Yingying Ding, Rongbiao Ying, Jiage Ma, Qiqi Ren
DOI: 10.1039/d6fo00474a
Cited by: 4
References: 74

Abstract

. The contents of short-chain fatty acids were upregulated following 2'-FL + BB536 supplementation. Overall, 2'-FL combined with BB536 exerted alleviating effects on loperamide-induced constipation and depressive-like behavior through regulating the gut-brain axis.

Fields of Study & Subjects

Gastrointestinal motility and disorders Gut microbiota and health Probiotics and Fermented Foods

Publication details

Journal / source
Food & Function
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
13
Pages
5918–5938
Publication date
1 January 2026
Language
EN