Probiotic Lactobacillus kefiranofaciens K6 attenuates physiological and behavioral alterations and modulates the gut microbiota in a mouse model of overtraining syndrome
Abstract
may also provide potential benefits in the Exercise group. Excessive training stress in this experimental OTS-like mouse model was associated with multiple metabolic, inflammatory, behavioral, and microbiota-related disturbances, whereas K6 supplementation was associated with attenuation of several OTS-related alterations. These findings suggest that microbiota-targeted nutritional strategies may support physiological resilience under excessive training stress; however, the results should be interpreted as associative and hypothesis-generating, as mechanistic relationships were not directly examined.
Fields of Study & Subjects
Gut microbiota and health
Probiotics and Fermented Foods
Infant Nutrition and Health
Publication details
- Journal / source
- Food & Function
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 17
- Issue
- 11
- Pages
- 4988–5005
- Publication date
- 1 January 2026
- Language
- EN