Daily supplementation with egg yolk lipids from two eggs alleviated cognitive impairment in 5 × FAD mice by restoring neuronal and synaptic function and regulating gut microbiota

Food & Function 2026

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Authors: Le Cheng, Yifei Wang, Yumeng Ma, Chenyan Zheng, Zihan Wang, Fang Wu, Bing Fang
DOI: 10.1039/d6fo00928j
Cited by: 1
References: 39

Abstract

DHA-enriched egg yolk lipids (two eggs daily) alleviate 5 × FAD mouse cognitive deficits by promoting neuronal survival, improving synaptic plasticity, suppressing neuroinflammation, and remodeling gut microbiota and neuroprotective metabolites.

Fields of Study & Subjects

Phytoestrogen effects and research Nutritional Studies and Diet Protein Hydrolysis and Bioactive Peptides

Publication details

Journal / source
Food & Function
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
12
Pages
5690–5703
Publication date
1 January 2026
Language
EN