A bioinspired photoenzymatic cascade enabled by a bifunctional arylformamidase for efficient synthesis of l -kynurenine derivatives

Green Chemistry 2026

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Authors: Changmei Liu, Xiaorui Chen, Chengyue Miao, Changtong Zhu, Meiling Liu, Min He, Xinpeng Lu, Wenrui Huang, Yijian Rao, Zhenbo Yuan
DOI: 10.1039/d6gc00950f
Cited by: 3
References: 63

Abstract

A bioinspired one-pot one-step photoenzymatic cascade integrating a metal-free photocatalyst and an engineered bifunctional arylformidase directly convert l -Trp and its esters into l -Kyn under mild conditions with excellent green metrics evaluation.

Fields of Study & Subjects

Tryptophan and brain disorders Fluorine in Organic Chemistry Psychedelics and Drug Studies

Publication details

Journal / source
Green Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
28
Issue
15
Pages
6680–6690
Publication date
1 January 2026
Language
EN