Process-intensified enzymatic decarboxylation using immobilized arylmalonate decarboxylase for sustainable asymmetric synthesis of α-arylpropionic acids

Green Chemistry 2026 Open access

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Authors: Jan Gerstenberger, Timm Werbilo, Marvin Haas, Simona Şerban, Alessandra Basso, Pablo Domínguez de María, Selin Kara
DOI: 10.1039/d6gc02400a
Cited by: 1
References: 70

Abstract

Integrating alkaline saponification with enzymatic decarboxylation in a pH-stat rotating bed reactor suppresses racemic side reactions via anionic stabilization, ensuring high enantiopurity as a green alternative to hydrogenolysis.

Fields of Study & Subjects

Biochemical and biochemical processes Enzyme Catalysis and Immobilization Biochemical Acid Research Studies

Publication details

Journal / source
Green Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
28
Issue
29
Pages
12087–12100
Publication date
1 January 2026
Language
EN