Porous microneedle-based electrochemical aptamer biosensor for the collection and quantitative analysis of dry eye disease biomarkers
Abstract
in tears, which are above the detection limits of our sensors. By taking MMP-9 as a model biomarker, we demonstrate a complete collection-to-detection workflow using this microneedle-aptamer biosensing device, which would facilitate the realization of point-of-care monitoring of DED.
Fields of Study & Subjects
Ocular Surface and Contact Lens
Advanced Drug Delivery Systems
Advancements in Transdermal Drug Delivery
Publication details
- Journal / source
- Lab on a Chip
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 26
- Issue
- 10
- Pages
- 3002–3012
- Publication date
- 1 January 2026
- Language
- EN