Novel hydroxytyrosol esters as potential anti-amyloid and neuroprotective agents for Alzheimer's disease

RSC Medicinal Chemistry 2026 Open access

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Authors: Ioanna Kalpaktsi, Anthi Panara, Barbara Mavroidi, Garcia Niforos, Amalia D. Kalampaliki, Ioanna C. Vlachogianni, Eleftheria A. Georgiou, Elizabeth Fragopoulou, Anthony Tarbopoulos, Alexios‐Léandros Skaltsounis, Maria Pelecanou, K Palikaras
+2 more Evagelos Gikas, Ioannis K. Kostakis
DOI: 10.1039/d6md00265j
Cited by: 1
References: 42

Abstract

Hydroxytyrosol-derived esters emerge as stable oleuropein mimetics that inhibit Aβ aggregation and confer in vivo neuroprotection.

Fields of Study & Subjects

Phytochemicals and Antioxidant Activities Free Radicals and Antioxidants Cholinesterase and Neurodegenerative Diseases

Publication details

Journal / source
RSC Medicinal Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
7
Pages
3297–3312
Publication date
1 January 2026
Language
EN