Synthesis and structural elucidation of a trifluoromethylated cyclopentene hydrazone: a combined X-ray and computational study

New Journal of Chemistry 2026

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Authors: Elizaveta V. Panova, Bakhtiyor Sh. Ganiev, Kuvondik G Avezov, Bako B. Umarov, Julia Konstantinovna Voronina, Damir Amirovich Safin
DOI: 10.1039/d6nj00632a
Cited by: 1
References: 66

Abstract

We report on benzoylhydrazo-2-trifluoroacetylcyclopent-1-ene ( 1 ), which structural and electronic properties were studied, and a prediction was made regarding its potential activity against hemoglobin S, which is a key protein in sickle cell anemia.

Fields of Study & Subjects

Phosphorus compounds and reactions Fluorine in Organic Chemistry Synthesis and Characterization of Pyrroles

Publication details

Journal / source
New Journal of Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
50
Issue
17
Pages
7490–7504
Publication date
1 January 2026
Language
EN