Ortho -alkyl phenylalkenoyl natural products: structural diversity, bioactivities and biosynthesis
Abstract
, isomerization, 6π-electrocyclisation) and multifunctional enzymes, providing valuable biocatalysts for synthetic biology. Although their biological activities depend strongly on structural context, emerging evidence highlights these metabolites as a promising source of lead compounds. Continued interdisciplinary efforts integrating natural product chemistry, biosynthesis, and medicinal chemistry are expected to unlock their therapeutic potential.
Fields of Study & Subjects
Microbial Natural Products and Biosynthesis
Plant biochemistry and biosynthesis
Marine Sponges and Natural Products
Publication details
- Journal / source
- Natural Product Reports
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 43
- Issue
- 10
- Pages
- 2049-2083
- Publication date
- 1 January 2026
- Language
- EN