Influence of particle size, shape, and magnetic properties on torque-driven biofilm removal using anisotropic magnetic particles
Abstract
anisotropic magnetic particles (AMPs). Microrods, nanochains, and nanorods with distinct sizes and magnetic properties were actuated under identical RMF conditions on implant-relevant titanium substrates. Micron-scale magnetic microrods generate sufficient magnetic torque to mechanically disrupt the EPS matrix and detach biofilm structures, significantly increasing suspended bacterial cells without marked bactericidal effects. In contrast, nanoscale AMPs do not induce biofilm detachment but cause membrane damage, increasing the proportion of injured cells. These findings demonstrate a size-dependent transition between microscale biofilm detachment and nanoscale membrane interactions, identifying particle size as the dominant parameter governing magneto-mechanical biofilm disruption.
Fields of Study & Subjects
Bacterial biofilms and quorum sensing
Nanoparticle-Based Drug Delivery
Micro and Nano Robotics
Publication details
- Journal / source
- Nanoscale
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 18
- Issue
- 19
- Pages
- 10203–10214
- Publication date
- 1 January 2026
- Language
- EN