Defect engineering of VN nanowires enables dual-mode SERS-colorimetric quantification of glutathione in serum
Abstract
0.6 mM), with both values aligning within established clinical reference ranges. Density functional theory (DFT) calculations revealed that the SERS enhancement mechanism of P-VN@C stems from its superior charge transfer capability (0.4653 e per unit), representing an 8.4-fold increase over the undoped system (0.0554 e per unit). This work provides a novel material design strategy for developing high-performance, non-precious-metal-based sensors in clinical diagnostics.
Fields of Study & Subjects
Sulfur Compounds in Biology
Advanced Nanomaterials in Catalysis
Gold and Silver Nanoparticles Synthesis and Applications
Publication details
- Journal / source
- Nanoscale
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 18
- Issue
- 24
- Pages
- 13097–13108
- Publication date
- 1 January 2026
- Language
- EN