A three-component 1,3-dipolar cycloaddition of pyrazolone-derived azomethine ylides with succinimides for the construction of novel spiro-pyrazolone-pyrrolizines containing succinimides

Organic & Biomolecular Chemistry 2026

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Authors: Jianming Xu, Dan Hu, Jian Wang, Song Hu, Heng Yin, Yulong Li, Chen‐Yi Li
DOI: 10.1039/d6ob00014b
Cited by: 0
References: 82

Abstract

from pyrazolediones and prolines has been developed, and a series of novel pharmaceutically interesting spiro-pyrazolone-pyrrolizines containing succinimides was obtained in moderate to excellent yields with poor to excellent diastereoselectivities.

Fields of Study & Subjects

Multicomponent Synthesis of Heterocycles Asymmetric Synthesis and Catalysis Chemical synthesis and pharmacological studies

Publication details

Journal / source
Organic & Biomolecular Chemistry
Volume
24
Issue
6
Pages
1363–1368
Publication date
1 January 2026
Language
EN