An isocoumarin route to resorcylic acid lactones (RALs): asymmetric total synthesis of neocosmosin A, fusariumin and penicipyran D

Organic & Biomolecular Chemistry 2026

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Authors: Kishor Kumar Mandal, Samik Nanda
DOI: 10.1039/d6ob00143b
Cited by: 1
References: 32

Abstract

cyclization of penta-substituted 2-alkynylated benzoates. An improved synthesis of neocosmosin A was also established through a late-stage RCM reaction from an isocoumarin-derived advanced intermediate.

Fields of Study & Subjects

Synthesis and Biological Activity Synthesis and pharmacology of benzodiazepine derivatives Plant chemical constituents analysis

Publication details

Journal / source
Organic & Biomolecular Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
24
Issue
11
Pages
2324–2331
Publication date
1 January 2026
Language
EN