Linker dependence of 1 O 2 generation by G4-binding tetra-imidazolium porphyrins

Organic & Biomolecular Chemistry 2026 Open access

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Authors: Çetin Çelik, Naoko Kakusho, Tianyu Xu, Sung Hwa Lee, Naoko Yoshizawa-Sugata, Hisao Masai, Yoko Yamakoshi
DOI: 10.1039/d6ob00581k
Cited by: 1
References: 36

Abstract

generation was enhanced. Cellular internalization of these porphyrins was observed by flow cytometry, resulting in sufficient photocytotoxicity of these porphyrins toward both cancer cells (HeLa) and normal cells (NHDF). Photocytotoxicity to a cancer cell line was higher than that to normal cells. Although this mechanism was not clearly explained, the results show superior properties of these porphyrin molecules reported here as PDT-PSs.

Fields of Study & Subjects

Porphyrin and Phthalocyanine Chemistry DNA and Nucleic Acid Chemistry Photodynamic Therapy Research Studies

Publication details

Journal / source
Organic & Biomolecular Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
24
Issue
24
Pages
5028–5036
Publication date
1 January 2026
Language
EN