Bis(cyclooctadiene)nickel(0)-catalyzed exhaustive C(sp 2 )–X and C(sp 3 )–F hydrodehalogenation and deuterodefluorination of pyridines and arenes with a broad substrate scope
Abstract
The exhaustive HDH and DDH of CF 3 groups in pyridines and the HDH of C(sp 2 )–X (X = F, Cl, Br, and I) bonds in pyridines and arenes were catalyzed by [Ni(COD) 2 ] using NH 3 BH 3 (for HDH) or ND 3 BD 3 (for DDH) and KO t Bu at room temperature.
Fields of Study & Subjects
Fluorine in Organic Chemistry
Catalytic C–H Functionalization Methods
Environmental remediation with nanomaterials
Publication details
- Journal / source
- Inorganic Chemistry Frontiers
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 13
- Issue
- 7
- Pages
- 3079–3095
- Publication date
- 1 January 2026
- Language
- EN