Electronic modification of hexa-2,4-diyne-1,6-diols: predictive access to strained cyclobutenes and 3(2 H )-furanones

Organic Chemistry Frontiers 2026

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Authors: Seyed Mohammad-Bagher-Hosseini Ghazvini, Diego Cordova Mariño, Ingrid Dell, Elena Dallerba, Carol Hua, Paul J. Low, Massimiliano Massi, Marcus Korb
DOI: 10.1039/d6qo00056h
Cited by: 1
References: 94

Abstract

Electronically diverse hexa-2,4-diyne-1,6-diols enable predictive switching between dibromocyclobutene/butafulvene and 5-vinyl-3(2 H )-furanone synthesis. The latter are preferred for electron-poor substrates, and were further turned into fluorophores.

Fields of Study & Subjects

Cyclization and Aryne Chemistry Synthesis and Properties of Aromatic Compounds Catalytic Alkyne Reactions

Publication details

Journal / source
Organic Chemistry Frontiers
Publisher
Royal Society of Chemistry (RSC)
Volume
13
Issue
10
Pages
3007–3020
Publication date
1 January 2026
Language
EN