α-Functionalization of ethers with acridanes and amines via metal-free direct C(sp 3 )–H radical–radical cross-dehydrogenative coupling
Abstract
A metal-free radical–radical cross-dehydrogenative coupling of the relatively inert C(sp 3 )–H bond of ethers with the C(sp 3 )–H bond of acridanes and amines has been developed, enabling the synthesis of C9-etherified acridanes and α-etherified amines.
Fields of Study & Subjects
Catalytic C–H Functionalization Methods
Radical Photochemical Reactions
Catalytic Cross-Coupling Reactions
Publication details
- Journal / source
- Organic Chemistry Frontiers
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 13
- Issue
- 8
- Pages
- 2437–2443
- Publication date
- 1 January 2026
- Language
- EN