Visible-light-driven radical cascade cyclization of 4-( N -alkyl- N -acrylamido)coumarins: access to difluoroalkylated 4,5-fused coumarins and coumarin[4,3- b ]pyridinones

Organic Chemistry Frontiers 2026

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Authors: Jinwei Yuan, Shi-Long Zhang, Xin-Ya Wang, Meng Yan, Yongmei Xiao, Donghui Wei, Lingbo Qu
DOI: 10.1039/d6qo00192k
Cited by: 1
References: 88

Abstract

An efficient and practical visible-light-driven cascade difluoroalkylation/cyclization of 4-acrylaminocoumarins has been developed using readily accessible [Ph 3 PCF 2 H] + Br − as the difluoroalkyl radical precursor.

Fields of Study & Subjects

Radical Photochemical Reactions Fluorine in Organic Chemistry Catalytic C–H Functionalization Methods

Publication details

Journal / source
Organic Chemistry Frontiers
Publisher
Royal Society of Chemistry (RSC)
Volume
13
Issue
10
Pages
3074–3082
Publication date
1 January 2026
Language
EN