Redox-neutral assembly of diheteroarylalkanes via transient directing group-enabled C–H methylenation

Organic Chemistry Frontiers 2026

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Authors: Xuemeng Wang, Liqing Xu, Kexin Ma, Yiyan Hong, Chuan Fu, Kai Teng Tan, Dong Wang
DOI: 10.1039/d6qo00215c
Cited by: 3
References: 43

Abstract

We report a transient directing group strategy for direct assembly of diheteroarylalkanes via regioselective C(sp 2 )–H methylenation using Eschenmoser's salt, demonstrating broad substrate scope under mild, redox-neutral conditions.

Fields of Study & Subjects

Catalytic C–H Functionalization Methods Radical Photochemical Reactions Catalytic Cross-Coupling Reactions

Publication details

Journal / source
Organic Chemistry Frontiers
Publisher
Royal Society of Chemistry (RSC)
Volume
13
Issue
10
Pages
3115–3122
Publication date
1 January 2026
Language
EN