Cycloaddition/ring-opening cascade reaction of alkylidene azlactones for the synthesis of α,α-disubstituted α-amino acid esters

Organic Chemistry Frontiers 2026

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Authors: Jyoti Sikarwar, Jyoti Chauhan, Rama Krishna Peddinti
DOI: 10.1039/d6qo00556j
Cited by: 1
References: 58

Abstract

Solvent-controlled, metal-free diastereoselective cascade reaction between alkylidene azlactones and N -phenacylbenzothiazolium salts enabling efficient access to pyrrolo[2,1- b ]benzothiazole-based α,α-disubstituted α-amino acid esters is reported.

Fields of Study & Subjects

Synthesis and Reactions of Organic Compounds Synthesis and Characterization of Pyrroles Asymmetric Synthesis and Catalysis

Publication details

Journal / source
Organic Chemistry Frontiers
Publisher
Royal Society of Chemistry (RSC)
Volume
13
Issue
15
Pages
4787–4793
Publication date
1 January 2026
Language
EN