Tridentate PyMPAA ligands enable efficient Pd-catalyzed non-directed arene deuteration

Organic Chemistry Frontiers 2026 Open access

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Authors: Jiawei Han, Mengtao Zhu, Yu Meng, Tao Cen, Jian‐Fei Bai, Jia Chen, Zhi‐Jiang Jiang, Zhanghua Gao
DOI: 10.1039/d6qo00600k
Cited by: 1
References: 49

Abstract

We report a novel PyMPAA ligand for Pd-catalyzed non-directed hydrogen–deuterium exchange reactions, with successful application to various PAHs and drug molecules.

Fields of Study & Subjects

Chemical Reactions and Isotopes Asymmetric Hydrogenation and Catalysis Environmental remediation with nanomaterials

Publication details

Journal / source
Organic Chemistry Frontiers
Publisher
Royal Society of Chemistry (RSC)
Volume
13
Issue
16
Pages
5061–5067
Publication date
1 January 2026
Language
EN