Iodine-doped carbon dots for fluorescence/computed tomography imaging and photodynamic therapy of tumor cells
Abstract
investigations indicated that I-CDs were an effective nanophotosensitizer for the photodynamic therapy (PDT) of A549 and HeLa cells. Computed tomography (CT) scan data revealed that the Hounsfield unit (HU) value of I-CDs surpassed that of iohexol. Thereafter, the obtained I-CDs were successfully applied for performing the fast CT contrast imaging of mouse kidneys and bladders (within 1 minute); notably, I-CDs displayed negligible histopathological and hemolytic toxicity. I-CDs showed potential in the fields of fluorescence/CT bimodal imaging and PDT.
Fields of Study & Subjects
Carbon and Quantum Dots Applications
Nanoplatforms for cancer theranostics
Photodynamic Therapy Research Studies
Publication details
- Journal / source
- RSC Advances
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 16
- Issue
- 19
- Pages
- 17401–17414
- Publication date
- 1 January 2026
- Language
- EN