DNA aptamers that inhibit binding to human interleukin-17A and interleukin-20
Abstract
values as low as 120 nM. Photo-crosslinking experiments confirmed aptamer binding to its cytokine target, most likely to the cytokine monomer. These novel DNA aptamers for IL-17 and IL-20 represent valuable tools for studying cytokine biology and developing potential therapeutics for inflammatory and autoimmune conditions like psoriasis and impaired wound healing.
Fields of Study & Subjects
Advanced biosensing and bioanalysis techniques
DNA and Nucleic Acid Chemistry
Psoriasis: Treatment and Pathogenesis
Publication details
- Journal / source
- RSC Advances
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 16
- Issue
- 22
- Pages
- 20340–20346
- Publication date
- 1 January 2026
- Language
- EN